Contraindications and limitations to the use of Ambien zolpidem
Hypersensitivity, the age to 15 years. Pickwick’s syndrome, nocturnal apnea, violation of external respiration, myasthenia gravis, depressive states, alcohol dependence, substance abuse, drug dependence, severe hepatocellular insufficiency, severe renal dysfunction, elderly age.
|Drug Name||Doses||Per Pill||Visit Pharmacy|
|Generic Ambien||10 mg||$2.51|
Application in pregnancy and lactation
Studies of teratogenic effects on the human fetus have not been conducted. In experiments on rats, the effects of zolpidem on bone were the formation of the skull in rat fetus were revealed.
When pregnant women take Ambien before childbirth, the development of the withdrawal syndrome in a newborn is possible, which is characterized by increased excitability, muscle hypertension, lowering of the basic reflexes, tremor of the child’s limbs.
The drug belongs to category C by the FDA classification – it is possible to use the drug during pregnancy if the expected result of its use exceeds the risk of negative effects on the fetus. If zolpidem is necessary for a pregnant woman, then the treatment is carried out under the strict supervision of a doctor.
During treatment with cheap Ambien, it is necessary to buy Ambien online and suspend breastfeeding.
Side effects of Ambien
Negative effects of Ambien on the nervous system are manifested in the form of cephalalgia, pathological drowsiness, dizziness, antegrade amnesia, impaired coordination of movements, reduced concentration of attention, depressive states, drug intoxication, episodes of lethargy, unusual dreams, nightmares, agitation, nervous states, sleep disorders, Confusion, euphoria, speech disorders, emotional lability, hypersensitivity, paresthesia, hallucinatory manifestations, migraine, stupor, hand tremor, lethargy, bulimia, decreased libido, neuralgia, neuropathy, panic attacks, personality disorders, suicide attempts.
Negative manifestations of the gastrointestinal tract: diarrhea, constipation, vomiting, nausea, hiccough, gastroesophageal reflux, dry mouth, abdominal pain, impaired appetite.
Disorders from the respiratory system: there may be an infectious process in the respiratory tract in the form of sinusitis, pharyngitis, rhinitis.
From the side of the autonomic nervous system are possible: hyperhidrosis, pallor, hypotension, syncopal conditions, disruption of accommodation, xerostomia, glaucoma, impotence, tenesmus.
From the cardiovascular system: tachycardia, arterial hypertension, chest pain, angina pectoris, arrhythmia, myocardial infarction, phlebitis, arthritis, pulmonary embolism, pulmonary edema.
Hepatobiliary system: increased hepatic transferases, hyperbilirubinemia.
Violation of basal metabolism: hyperglycemia, thirst, gout, increased cholesterol, alkaline phosphatase, urea nitrogen in the blood.
Sexual system: disorders of the ovarian-menstrual cycle, vaginitis.
Genito-urinary system: inflammation of the bladder, enuresis, kidney failure, dysuric manifestations.
Other: chest pain, fatigue, muscle pain, back pain, arthralgia, ischialgia, rash on the skin, acne, itching, abrasions decreased immunity, urinary tract infection, edema, anemia, leukopenia, eye pain, double vision, distortion taste, otitis media. The side effects are dose-dependent.
Interaction of Ambien with other drugs
The possible additive effect of Ambien when co-administered with drugs affecting the central nervous system. Benzodiazepines increase the risk of drug dependence. It reduces the maximum concentration of imipramine and chlorpromazine half-life.
In the interaction with ketoconazole increases the maximum level of zolpidem in the blood plasma and its half-life. Such a reaction requires reducing the dose of sleeping pills.
When Ambien interacts with rifampicin greatly reduced the half-life of Ambien and its maximum concentration and, therefore, decreasing its pharmacological effects. In this case, you need a dose adjustment of sleeping pills.